A pathologist, Dr. Warren Chapin (played by Vincent Price), discovers that the tingling of the spine in states of extreme fear is due to the growth of a tingler—a spinal parasite which can kill the host unless it is destroyed by screaming.

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A pathologist, Dr. Warren Chapin (played by Vincent Price), discovers that the tingling of the spine in states of extreme fear is due to the growth of a tingler—a spinal parasite which can kill the host unless it is destroyed by screaming.